Frailty Index Study: A Challenge Study to Quantify Fatigue


Background: Frailty indices have been assessed worldwide using Index by the Fried et al. (2001). The index consists of five indicators: (1) unintentional weight loss, (2) self-reported fatigue, (3) weakness (grip strength), (4) slow walking speed, and (5) low physical activity. Of these, the self-reported fatigue index is a subjective assessment and may differ from objective assessments of physical and mental fatigue. There is a need to investigate whether subjective fatigue can be replaced by an objective measure. Purpose: We examine the relationship between subjective fatigue and indicators of chronic fatigue syndrome and to investigate factors that influence subjective fatigue. Methods: We measured a measure of autonomic nervous system activity in 1258 people. Result: Results Study 1: TP, ccvTP, LF and HF decrease with age; LF/HF (stress index) is independent of age. Study2-1: Fatigue, muscle mass and lean body mass are strongly negatively correlated. In relation to age and body composition, age and body fat percentage and fat mass, total body muscle score, muscle mass, estimated bone mass, and body water content showed a non-significant negative correlation. Study 2-2: There was a non-significant negative correlation between subjective fatigue and HF, LF/HF, TP and ccvTP. Study 2-3: There were correlations between subjective fatigue and muscle mass, lean body mass, bone mass, and body water content. Conclusions: Autonomic nervous system indices may be associated with subjective fatigue in Japanese older adults. The results suggest that subjective fatigue may be associated with body composition.

Author Information
Akemi Kariya, Asahigawaso Research Institute, Japan
Yoshio Fujimura, Biwako Professional University of Rehabilitation, Japan
Naoshi Isaka, Biwako Professional University of Rehabilitation, Japan
Katsuhiko Osaki, Biwako Professional University of Rehabilitation, Japan
Masako Morita, Mitsugi General Hospital, Japan
Masao Yamauchi, Biwako Professional University of Rehabilitation, Japan

Paper Information
Conference: EGen2023
Stream: Frailty

This paper is part of the EGen2023 Conference Proceedings (View)
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To cite this article:
Kariya A., Fujimura Y., Isaka N., Osaki K., Morita M., & Yamauchi M. (2023) Frailty Index Study: A Challenge Study to Quantify Fatigue ISSN: 2435-4937 The European Conference on Aging & Gerontology 2023: Official Conference Proceedings
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Posted by James Alexander Gordon