The Interaction Between Biological and Sociocultural Factors Increases Risk of Cancer in East Asian Alcohol Flushers

Abstract

One of the most common causes of human cancer is alcohol consumption. There has been evidence that shows drinking increases the risk of cancer in the mouth and throat, larynx, colon, liver, female breast, and especially the esophagus. However, much of the existing data is collected from Western countries. This literature review aims to evaluate the interaction between genetic influences, behaviors, and environments for the development of cancer through the consumption of alcohol in East Asian individuals. The targeted population was selected specifically for their unique facial flushing reaction after consuming alcohol. Alcohol flushing is an allergic response triggered mainly by the inactive aldehyde dehydrogenase-2 (ALDH2) genotype. Study participants range from adults in East Asian countries (China, Japan, and Korea) to college students with East Asian ethnicities in the United States. While previous research has suggested the association between ALDH2 inactive gene flushing response and alcohol-associated cancers, Asian flushers are more at risk due to social, psychological, and cultural influences on drinking behavior.



Author Information
Hoang H. Le, University of Washington, United States

Paper Information
Conference: ACP2023
Stream: General Psychology

This paper is part of the ACP2023 Conference Proceedings (View)
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To cite this article:
Le H. (2023) The Interaction Between Biological and Sociocultural Factors Increases Risk of Cancer in East Asian Alcohol Flushers ISSN: 2187-4743 – The Asian Conference on Psychology & the Behavioral Sciences 2023 Official Conference Proceedings (pp. 9-18) https://doi.org/10.22492/issn.2187-4743.2023.2
To link to this article: https://doi.org/10.22492/issn.2187-4743.2023.2


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Posted by James Alexander Gordon